If your definition of safe, is like “no one has even been fired for choosing IBM”, SAFe may be safe. Though, you really need to consider, will it help your organization improve? I hoped that Scrum would help the world discover iterative and incremental engineering practices and principles. It seems to me, it has failed. Maybe SAFe can be different; I don’t know.
I have not spent any time looking into SAFe. I cannot make an informed opinion. I would make my opinion based on the message of SAFe and how it is being adopted. Generally, I am critical of what most Agile adoptions have become, Agile in name only (AINO). AINO adoptions leave developers feeling like they are being micromanaged and pressured to do poor work.